(96 glt n/a 117k) My son quickly lost acceleration 5 min. into a trip and nursed the car home on the highway, bucking, choking,and almost stalling especially when going up hills. He said it didn't seem to shift up. Cel on : code p0300 (random, multiple misfires) came up plus 301, 302, 303 & 304. I changed plugs, rotor & cap last year when p0300 came up under same circumstance, and I don't believe all the plug wires would go at once so I figuered coil or coil wire might be the cause this time. However, I remembered how my truck is sensitive to moisture in the gas tank, and we had damp, foggy weather this week. He said there was only a few gallons in the tank and it wasn't driven all week. I filled it with good gas (I like Shell), put fuel conditioner in and 5 miles down the highway after it smoothed out I cleared the codes. Put another 20 miles on it; very responsive never skipping a beat, running great.
Hope he learns a lesson: don't make a habit of keeping just a little, cheap gas in the tank (yes, he ponied up for the tankful !)
My lesson: continue to check the easy stuff first (plenty of time to curse later)

 

You might want to check/change the fuel filter too, just in case. The lower the fuel level the harder the pump has to work pushing the fuel through the filter.

 

will change filter. it's due. thanks for the heads-up